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维生素A在神经母细胞瘤发生和治疗中的应用研究进展 被引量：2

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摘要 神经母细胞瘤（neuroblastoma．NB）是最常见的小儿恶性实体瘤，来源于未成熟的胚胎细胞，也即是胚胎时期未分化的干细胞向正常细胞分化过程中由于某些调控机制障碍．引起组织分化延滞或停顿，组织分化不良而导致肿瘤发生。维生素A是参与生物体胚胎发育、器官形成的重要物质。研究发现维生素A具有促进细胞分化的作用，而其在体内代谢的衍生物维甲酸也具有控制细胞分化增生和凋亡的能力。
作者 刘胜勇 王忠荣
机构地区 安徽医科大学附属省立医院儿外科
出处 《实用医学杂志》 CAS 2008年第13期2358-2359,共2页 The Journal of Practical Medicine
关键词 神经母细胞瘤 维生素A 小儿恶性实体瘤 治疗 胚胎细胞 组织分化 细胞分化 分化过程
分类号 R739.41 [医药卫生—肿瘤]
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参考文献18

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共引文献10

同被引文献18

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实用医学杂志
2008年 第13期

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