摘要
静脉注射吗啡(02mg/100g),能降低大鼠心肌缺血后再灌注心律失常的发生率,并可降低再灌注心肌脂质过氧化物(MDA)的含量。提示吗啡对心肌缺血后再灌注损伤有保护作用。
出处
《广州医药》
1997年第6期57-58,共2页
Guangzhou Medical Journal
同被引文献12
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1赵建洪,程彦斌,张正义,纳涛.吗啡对大鼠急性心肌缺血/再灌注损伤的保护作用及其对心肌细胞凋亡的影响[J].第四军医大学学报,2004,25(16):1460-1463. 被引量:7
-
2刘睿,张岫美.阿片样物质参与心血管系统调控[J].中国药理学通报,2005,21(4):497-500. 被引量:6
-
3肖安,薛采芳,魏保真,毕辉,张鹏,郭海涛,王跃民,裴建明.κ阿片受体在抗缺血/再灌注大鼠心律失常中的作用机制[J].中国药理学通报,2006,22(6):715-719. 被引量:8
-
4Yvon A, Hanouz JL, Terrien X, et al. Electrophysiological effects of morphine in an in vitro model of the 'border zone' between normal and ischaemicreperfused guinea-pig myocardium. British Journal of Anaesthesia, 2002, 89: 888-895.
-
5Priori SG, Corr PB. Mechanismsunderlying early and delayed after depolarizations induced by cate-cholamines. Am J Physiol, 1990,258: H1796-H1805.
-
6Song Y, Thedford S, Lerman BB, et al. Adenosine-sensitive after depolarizations and trig-gered activitying uinea pig ventricular myocytes. Circ Res, 1992,70 : 743-753.
-
7Xia Q, Tai KK, Wang TM. Chronic morphine treatment increases the number , but decreases the affinity of u69593 binding sites in the rat heart. Life Sci, 1992,50:1143-1148.
-
8Schultz JE, Hsu AK, Gross GJ. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart. Circ Res 1996,78:1100-1104.
-
9Schwartz LM,Jennings RB, Reimer KA. Premedication with the opioid analgesic butorphanal raises the threshold for ischemic preconditioning in dogs. Basic Res Cardiol, 1997,92: 106-114.
-
10Wong TM, Lcc AYS. Chronic Morphine treatment reduced the ventricular arrhythmias in the isolated rat heart induced by dynorphin or myocardial inchacmia and reperfusion. Ncurosci Lett, 1987,77 : 61-65.
-
1周滨尔,徐洪军.辅酶Q10对心肌缺血后再灌注损伤的保护作用[J].苏州医学院学报,1996,16(5):833-834.
-
2农慧.中医药治疗心肌缺血及缺血后再灌注损伤动物实验研究[J].实用中医内科杂志,2004,18(5):393-394.
-
3郑信华,赵华月,郭志凌.镁盐对狗心肌缺血/再灌注损伤的防治作用及其机理研究[J].中国冶金医学杂志,1993,10(4):193-197. 被引量:3
-
4程时,赵宝路,忻文娟,唐朝枢,李兆萍.离体大鼠心肌缺血后再灌注损伤及其保护[J].中国循环杂志,1990,5(4):322-324. 被引量:6
-
5谢赟,陈寿权,李章平.中药对心肌损伤保护作用的研究进展[J].中西医结合心脑血管病杂志,2007,5(10):980-981. 被引量:3
-
6程时,刘智,王之湄,買鸿宴,李兆萍,唐朝枢.金属硫蛋白对大鼠心肌缺血后再灌注损伤的影响——电镜形态计量学研究[J].北京医科大学学报,1989,21(2):101-1. 被引量:13
-
7许敏,陈冬云,殷惠群,张根葆.核黄素对异丙肾上腺素所致的缺血后再灌注损伤大鼠心肌的保护作用[J].皖南医学院学报,2006,25(4):260-262.
-
8刘宗军,江智文,温沁竹,孙宝贵,尚孝堂,江蓓湖.再灌注损伤对大鼠心肌细胞凋亡的影响[J].中国心血管杂志,1999,4(4):222-223.
-
9赵勤勤,侯静波.CTRP9与急性冠脉综合征关系的研究进展[J].临床心血管病杂志,2016,32(2):119-122. 被引量:6
-
10董念国,蓝鸿钧.控制性再灌注对缺血心肌的保护作用[J].临床心血管病杂志,1994,10(3):187-189.