广州地区人群乙型肝炎流行特点与启示

Prevalent characteristis of hepatitis B and apocalypse in Guangzhou region population

目的分析描述广州地区人群乙型肝炎流行特点及其对乙肝预防工作的启示。方法针对广州地区三组特定人群用Elisa方法检测乙肝标志物并统计结果。结果广州地区人群HBsAg阳性率呈逐年下降趋势,人群中年轻一代较年长者HBsAg阳性率有逐步降低的倾向,但在少年儿童中对HBV缺乏免疫力的比例仍达48.90%。结论在少年儿童中必须监测乙肝疫苗免疫后的应答情况,使其对预防HBV感染真正发挥作用。

Objective To analyse the prevalent characteristic of hepatitis B in Guangzhou region population and its apocalypse to the preventive work. Methods HBV mark were examined by using ELISA method and the results were analyzed statistically in the three groups of particulor poputation in Guangzhou region. Results The HBsAg positive rate in population of Guangzhou region presented a descent trend year by year. The HBsAg positive rate in the young generation was more lower than that in the elderly. But the proportion of lack of HBV immunity in young children reached to 48.90%. Conclusion The immunity response to hepatitis B vaccine should be monitored in young children, make it play role in preventive work of HBV.