手术治疗对阻塞性睡眠呼吸暂停低通气综合征患儿生活质量的影响

Effect of surgical treatment on quality of life in children with obstructive sleep apnea hypopnea syndrome

目的探讨阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea hypopnea syndrome OSAHS）对患儿生活质量的影响，以及手术前后生活质量变化。方法对105例患儿进行儿童OSAHS疾病特异性生活质量调查（disease—specific quality of life for children with obstructive sleep apnea 18 items survey，OSA-18）和多导睡眠监测（polysomnography，PSG），分析两者的相关性，术后3～18个月进行生活质量的随访。结果术前OSAHS对患儿生活质量造成严重影响者占61．90％。术后得到明显改善，术后3个月总评分〉80者降至12．58％，18个月时降至4．76％。结论OSAHS患儿行腺样体或扁桃体切除术后，PSG指标显著改善和生活质量明显提高，并发现术后0SA-18量表评分与PSG检测指标间有明显相关性。

Objective To evaluate the influence of obstructive sleep apnea hyponea syndrome （OSAHS） on quality of life （QOL） in children and changes of QOL caused by surgical operation. Methods Pediatric OSAHS disease-specific quality of life survey （OSA-18 ） and polysomnngraphy （PSG） were applied to 105 children with OSAHS. They were given adenoidectomy and/or tonsillectomy, and followed up 3 to 18 months postoperatively. Results The impact of OSAHS on QOL was severe in 61. 90 % of pediatric patients. After surgery, their QOL got significantly improved. The ratios of the cases with total score of QOL greater than 80 dropped to 12. 58% and 4. 76% at 3 months and 18 months after operation. Conclusion The QOL and PSG indexes in children with OSAHS get improved dramatically after adenoidectomy or tonsillectomy. The OSA-18 scores are evidently associated with PSG indexes.