基于MRI的老年人丘脑体积的研究

Study of volume of thalamus on MRI from old people

目的利用立体定向MRI资料重建丘脑测量体积,分析年龄、性别对其的影响。方法选取健康成年自愿者行立体定向MRI扫描,在MRI上对丘脑进行识别、分割、提取、匹配与三维重建,测量重建后丘脑的体积。结果三维重建的丘脑表面光滑、形态逼真,清晰的显示了丘脑在标准立体定向空间中的位置,可直观显示,任意角度浏览。60岁以下组为(6089·66±105·13)mm3,60岁以上组丘脑平均体积为(5799·92±106·58)mm3。结论60岁以上组丘脑体积较60岁以下组显著缩小。

Objective To study the volume of thalamus with the help of magnetic resonance imaging （MRI） to analyze the effect of age and sex on it. Methods All the basic data from thalamus on stereotactic MRI from healthy volunteers,thalamus were identified, seg- mented, extracted, saved and 3D reconstructed. Results The surfaces of thalamus after 3D reconstruction were smooth and their shapes was clear and their morphosis was observed intuitively. Volume of the thalamus in over age of 60 was （5 799. 92 ± 106. 58） mm3, that in under age of 60 was （6 089.66 ± 105. 13） mm3. Conclusions The volume of thalamus in over the age of 60 diminutions apparently.