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原发性高血压对急性心肌梗死患者住院预后的影响 被引量:15

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摘要 目的探讨原发性高血压是否为影响急性心肌梗死(AMI)患者住院病死率的独立危险因素。方法回顾分析2136例 AMI 患者,比较原发性高血压和非原发性高血压组患者的临床特征、住院治疗和并发症发生率,并对可能影响 AMI 患者住院病死率的因素进行多因素回归分析。结果与无原发性高血压组相比,原发性高血压组患者年龄较大(64.6±10.6比61.8±12.2岁,P<0.01),女性较多(34.9%比25.6%,P<0.01),多伴有糖尿病(25.5%比20.5%,P<0.01)和高血脂症(63.3%比57.2%,P<0.01),有吸烟史者较少(47.8%比58.0%,P<0.01),住院期间抗血小板药物的使用率较低(97.0%比98.7%,P<0.01),β受体阻滞剂、血管紧张素转换酶抑制剂(ACEI)或血管紧张素受体拮抗剂(ARB)类药物的使用率较高(分别为73.6%比65.7%,P<0.01;80.1%比76.2%,P=0.032)。原发性高血压组患者住院病死率显著高于无原发性高血压组(10.3%比5.9%,P<0.01)。多因素回归分析显示年龄、原发性高血压、糖尿病、高血脂症和β受体阻滞剂的使用率均为影响 AMI 患者住院病死率的独立危险因素。结论原发性高血压是影响 AMI 患者住院病死率的独立危险因素。
出处 《中华高血压杂志》 CAS CSCD 北大核心 2008年第7期651-652,共2页 Chinese Journal of Hypertension
基金 山东省科学技术发展重点项目(2002BB1CJA1)
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参考文献6

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