山羊内毒素性DIC病症中血红细胞和氧自由基代谢的变化

Changes in Red Cells and Metabolism of Oxygen Free-radicals in Enterotoxigenic DIC Goats

用内毒素诱导建立山羊ＤＩＣ模型，检测血红细胞、ＳＯＤ和ＭＤＡ的变化，结果表明，模型组血红细胞聚集指数和血浆粘度下降，ＳＯＤ活力显著下降，ＭＤＡ含量显著上升，提示ＤＩＣ时存在血红细胞变形和氧自由基损伤。

DIC model of goat was developed using enterotoxigen induction and changes of red cells,SOD and MDA was also investigeted.It was found that the aggregation index of red cells,viscosity of plasma and SOD activity of treated goats decreased significantly while MDA content increased significantly,suggesting misshape of red cells and damage of oxygen free radicals in DIC goats.