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抗2型糖尿病药物——Alogliptin 被引量:7

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作者 王珊 范鸣
出处 《药学进展》 CAS 2008年第7期326-327,共2页 Progress in Pharmaceutical Sciences
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同被引文献26

  • 1Feng J,Zhang Z,Wallace MB,et al.Discovery of alogliptin:A potent,selective,bioavailabe,and efficacious inhibitor of dipeptidyl peptidase IV[J].J Med Chem,2007,50(10):2297-2300.
  • 2Serradell N,Rose E,Bolos J.Alogliptin benzoate[J].Drug Future,2008,33(1):7-12.
  • 3Feng J,Gwaltney SL,Stafford JA,et al.Dipeptidyl peptidase inhibitors:WO,2007035629[P].2006,9,15.
  • 4For method of determin ingex-vivoDPP-4 inhibition in plasma, see:Villhauer, E.B.;Brinkman, J.A.;Naderi, G.B.;Burkey, B.F.;Dun- ning, B.E.;Kapa, P.;Mangold, B.L.;Russell, M.E.;Hughes, T.E. 1 - [[(3 -Hydroxy -1 -adamantyl)amino]acetyl] -2 -cyano -(S ) -pyrro - lidine:Apotent,selective,and orally bioavailable dipeptidyl pepti- dase IV inhibitor with antihyperglycemic properties.J.Med.Chem. 2003,46: 2774-2789.
  • 5Gwahney, S.L., II;Stafford, J.A.Inhibitors of dipeptidyl peptidase 4.Annu.Rep.Med.Chem.2005,40: 149-165.
  • 6武田药品工业株式会社.包含阿格列汀和盐酸二甲双胍的固体制制[P].中国专利:10801351A,2010-08-11.
  • 7Radek Jurok,Radek Cibulka,Hana Dvorakova et al.Planar chiral flavinium salts-prospetive catalysts for enantioselective sulfoxidation reactions[J].European Journal of Organic Chemistry,2010,27:5217-5224.
  • 8Li Peng,Wu Haiyan.Organic compounds[P].WO133261,2006-6-6.
  • 9TOMOKO A, YUSUKE M, OSAMU K. A novel dipeptidyl peptidase-4 inhibitor, alogliptin ( SYR-322 ) , is effective in diabetic rats with sulfonylurea-induced secondary fail- ure [ J ]. Life Sci. , 2009,85 ( 2 009 ) : 122-126.
  • 10PRATLEY R E. Alogliptin:a new,highly selective dipep- tidly peptidase-4 inhibitor for the treatment of type 2 dia- betes [ J ]. Expert Opin. Pharmacother. , 2009, 10 ( 3 ) : 503-512.

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