轴不稳定手性配体的开发及其在不对称催化反应中的应用

Development of Axial-unfixed(Tropos) Ligands and Their Applications to Asymmetric Catalytic Reactions

轴不稳定配体应用于不对称催化有其独到的特点,不同于传统的轴稳定手性配体.综述了轴不稳定的噁唑啉、双膦、单膦、双羟基及N—O等配体的开发及其在不对称催化中的应用.

Tropos ligands, compared with traditional atropos ligands, have unique characteristics. Here, the development of several major types of tropos ligands, including oxazoline, biphosphine, monophosphine, bihydroxyl and N--O ligands, and their applications to asymmetric catalysis are reviewed.