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解脲支原体与男性不育之间的关系及其机制 被引量:6

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摘要 解脲支原体(ureaplasma urealyticum,UU)是一种介于细菌与病毒之间的原核微生物,是泌尿生殖道常见的条件致病病原体,从多方面损害人类生育能力,可引起男性不育,其机制可能通过黏附作用使精子膜缺损而改变精子形态、活力;通过细胞因子、微量元素的改变影响精子的发生、发育、成熟、获能等过程;通过交叉抗原产生的免疫应答干扰精卵结合,影响受精。UU并非都具有致病性,可存在于无症状携带者,UU致病力可能受血清型、浓度、时间、宿主状态等多方面因素的影响。
出处 《国际生殖健康/计划生育杂志》 CAS 2008年第4期230-233,共4页 Journal of International Reproductive Health/Family Planning
基金 浙江省医药卫生科学研究基金项目(编号:2007A200)
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