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子宫内膜异位症患者血管内皮生长因子的表达及其临床意义 被引量：1

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摘要 目的探讨血管内皮生长因子(VEGF)在子宫内膜异位症(EM)发生发展中的作用及其临床意义。方法用SP法检测EM患者36例异位内膜、32例在位内膜和22例正常子宫内膜组织中VEGF的表达情况。结果(1)VEGF蛋白在正常内膜、异位内膜和在位内膜组织中阳性表达率依次升高。(2)异位内膜组和在位内膜组分泌期VEGF表达强于增生期,差异有统计学意义(P<0.05),对照组增生期和分泌期表达强度均较弱,差异无统计学意义(P>0.05)。(3)分泌期VEGF表达,在位和异位内膜强于对照组,在位和异位内膜之间差异无统计学意义(P>0.05);增生期VEGF表达,三组内膜之间差异无统计学意义(P>0.05)。结论VEGF的表达异常与EM的发病有关。
作者 韦明 雷志英
机构地区 广西田阳县人民医院 右江民族医学院
出处 《广西医学》 CAS 2008年第7期988-989,共2页 Guangxi Medical Journal
关键词 子宫内膜异位症 血管内皮生长因子 免疫组织化学
分类号 R711.71 [医药卫生—妇产科学] R392 [医药卫生—免疫学]
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参考文献8

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共引文献461

同被引文献11

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引证文献1

二级引证文献8

广西医学
2008年 第7期

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