老年胃肠道间质瘤的诊治特点分析

Diagnosis and Treatment of Senile Gastrointestinal Stromal Tumor

目的探讨老年胃肠道间质瘤的诊治特点,以期改善老年胃肠道间质瘤的预后。方法回顾性分析23例老年胃肠道间质瘤的诊治过程及其特点。结果23例老年胃肠道间质瘤患者均给予手术治疗,但术前均未能明确诊断。术后高危患者给予格列卫治疗。随访2年,2年死亡率为43.5%,复发率为52.1%,格列卫有效率为27.3%。结论老年胃肠道间质瘤术前诊断困难,术后复发及死亡率高,对格列卫治疗效果差,加强早期诊断可改善预后。

Objective To explore the features of diagnosis and treatment of senile gastrointestinal stromal tumor in order to improve the prognosis of patients. Methods The clinical data about diagnosis and treatment of 23 older patients with gastrointestinal stromal tumor were analyzed retrospectively. Results All 23 cases received operation, but none of them were diagnosed correctly before operation. The high risk patients with malignant tumor were given Glivee after operation. A 2-year follow up showed that the mortality rate was 43.5 % , recurrence rate was 52.1%, and effective rate of Glivee was only 27.3 %. Conclusions The diagnosis of senile gastrointestinal stromal tumor was difficult before operation. The effect of Glivee was poor with high postoperative mortality and recurrence rate, The good prognosis could be improved by early diagnosis.