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血管内皮细胞生长因子在糖尿病性视网膜病变进展中的作用 被引量:8

Role of vascular endothelial growth factor in the progress of diabetic retinopathy
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摘要 糖尿病性视网膜病变是糖尿病微血管病变常见而严重的并发症,在很大程度上导致不可逆的视功能损害或完全失明.VEGF在DR发生、发展,尤其在视网膜新生血管形成过程中发挥重要作用,本文就血管内皮生长因子与糖尿病性视网膜病变的关系进行综述。 Diabetic retinopathy (DR) is a common and severe complication of diabetic microangiopathy. To a large extent, it causes irreversible damage to the visual function or complete blindness. Vascular endothelial growth factor (VEGF) plays an important role in the development of DR and in the process of retinal neovascularization. In this article we reviewed relations between VEGF and DR.
作者 黎铧 胡竹林
出处 《国际眼科杂志》 CAS 2008年第5期990-993,共4页 International Eye Science
关键词 糖尿病性视网膜病变 血管内皮细胞生长因子 临床研究 治疗方法 diabetic retinopathy vascular endothelial growth factor
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  • 1李媛,卢艳.糖尿病视网膜病变早期发病机制研究进展[J].国际眼科杂志,2005,5(4):750-754. 被引量:40
  • 2张小玲,邱曙东,陈艳炯,孙文涛.糖尿病性视网膜病变发病机制研究进展[J].国际眼科杂志,2005,5(6):1239-1242. 被引量:59
  • 3李才锐,孙曙光,姜德咏,洪卫.银杏叶提取物治疗早期糖尿病视网膜病变观察[J].国际眼科杂志,2006,6(1):78-81. 被引量:36
  • 4QAURN T,XU Q,JOUSSEN A M,et al.VEGF-initialed blood-retinal barrier breakdown in early diabetes[J].Invest Ophthalmol Vis Sci,2001,42(10):2 408.
  • 5LIP P L,CHATTERJEE S,CAINE G J,et al.Plasma vascular endothelial growth factor,angiopoietin-2 and souble angiopoitein receptor tie-2 in diabetic retinopathy:effects of laser photocoagulation and angiotensin receptor blockade[J].Br J Ophthamol 2004,88(12):1 543.
  • 6CHA D R,KIM N H,YOON J W,et al.Role of vascular endothelial growth factor in diabetic nephropathy[J].Kidney Int,2000,58(suppl 77):104.
  • 7Jean-Claude Manputu,Genevieve Renier.Advanced glycation end products incresse,through a protein kinase C-dependent pathway,vascular endothelial growth factor expression in retinal endothelial cells Inhibitory effect of gliclazide.J Diabetes Complications,2002;16:284-293
  • 8Hammes,HP,Martin S,Federlin K,Geisem K,Browmlee M.Aminogun-anidine treatment inhibits the development of experimental diabetic retinopathy.Proc Nati Sci USA,1991;(88):11555-11558
  • 9Okada Y,Yamanaka I,Sakamoto T,Hats Y,Sassa Y,Yoshikawa H,Fujisawa K,Ishibashi T,Inomata H.Increased Expression of Angiotensin-convening Enzyme in Retinas of Diabetic Rats.Jpn J Ophthalmol,2001;45(6):585-591
  • 10Otani A,Takagi H,Suzuma K,Honda Y.Angiontesin Ⅱ potentiates vascular endothelial growth factor-induced angiogenic activity in retinal mirocapillary endothelial cells.Circ Res,1998;82:619-628

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