经纤维支气管镜介入治疗支气管结核合并肺不张

Fiberoptic Bronchoscopy Treatment of Bronchial Tuberculosis with Atelectasis

目的探讨经纤维支气管镜介入治疗支气管结核合并肺不张的有效性和安全性。方法62例支气管结核合并肺不张患者随机分为治疗组和对照组。对照组应用常规抗结核治疗,治疗组在常规抗结核治疗的基础上给予清醒镇静麻醉下经纤支镜多点针刺注射或经纤支镜球囊扩张术为主的介入治疗。结果治疗组强化期末及疗程结束时痰菌阴转率分别为64.86%和100.00%,高于对照组的34.78%和65.22%,经比较差异均有统计学意义;疗程结束时治疗组胸片不张病灶吸收效率为91.89%,高于对照组的69.57%,经比较差异均有统计学意义。病人对治疗的耐受性好,未发现与介入治疗有关的严重副反应。结论清醒镇静下经纤支镜介入治疗方法是治疗支气管结核合并肺不张的有效方法,可弥补全身化疗的不足,提高治愈率,清醒镇静麻醉方式提高了患者的依从性,此疗法无明显毒性反应,并发症少,安全性好,值得临床推广应用。

Objective To evaluate the effectiveness and safety of the intervention Fiberoptic bronchoscopy treatment of bronchial-pulmonary tuberculosis. Methods 62 cases of bronchial tuberculosis combined atelectasis were randomly divided into treatment and control groups. The control group was given conventional anti-tuberculosis treatment, while the treatment group in addition to the conventional anti-tuberculosis treatment bronchoscopy multi-point injection or acupuncture Branchofiberoscope balloon dilatation-based intervention therapy was given under conscious sedation anesthesia. Results The negative sputum conversion rates of treatment group at the “strengthen period” and at the end of treatment were 64.86% and 100.00%, respectively, and were higher than the control group （34.78% and 65.22%）. There were significant differences in treatment at the end of the treatment group of chest film does not The chest film showed the tuberculosis focus absorption rate of the treatment group, 91.89%, was significantly higher than that of the control group, 69.57%. Patients tolerated well to this treatment and showed no serious side effects. Conclusion Under conscious sedation Fiberoptic bronchoscopy treatment for bronchial pulmonary tuberculosis is effective, and has no serious side effect and can supplement for the lack of systemic chemotherapy.