摘要
目的:通过在眼科局麻手术中辅助镇痛的研究,发现其最佳的适应证、最优化的组合方式、应用方法,从而使患者手术过程更舒适。方法:将2006-01/2007-10我院眼科局麻手术300例,共5类,包括白内障超声乳化吸出人工晶状体植入术,玻璃体切割手术,斜视矫正手术,巩膜外冷凝加外垫压术,泪囊鼻腔吻合术,每类各60例,随机分为试验组和对照组,每组30例。每例患者术前im非麻醉性镇痛药盐酸奈福冸2mL,对照组im等量生理盐水。手术开始后手术医生和麻醉师共同观察患者对疼痛的耐受情况,术后患者的舒适度。结果:5类手术患者在手术过程中对疼痛的感受均显著降低,表现为从手术开始到手术结束患者的疼痛耐受评分与对照组比较均有差异,患者术中的舒适度和术后的满意度均有提高。不良反应少,主要为一过性头晕和恶心。结论:在眼科局麻手术中辅助镇痛的临床应用使得患者在手术过程消除紧张焦虑、疼痛域值提高,从而使患者手术过程舒适,又不影响手术效率及眼科局麻手术的其他优势,对于眼外肌手术或手术时间长的内眼手术效果更明显。
AIM. To study the relieve pain effect in ophthalmologic operation with un-narcotic analgesic, in order to get more comfortable duration.
METHODS： In the prospective, randomized, double blind study, 300 patients were divided into 5 groups： phacoemulsification, vitreous operation, orthopia, retina detachment, and dacryocystorhinostomy. Of 60 patients in each group, 30 patients were injected with nefopam and others with NS as control before operation. Both surgeon and anesthetist observed the change of pain.
RESULTS. Compared with controls, patients injected with nefopam got relieve pain and more comfortable duration in all 5 operation groups. A few adverse presentations like dizzy and nausea were observed.
CONCLUSION： Un-narcotic analgesic is effective to relieve pain in ophthalmologic operation, and operation can be more comfortable and efficient, especially for operation on extraocular muscle and long time operation.
出处
《国际眼科杂志》
CAS
2008年第7期1387-1389,共3页
International Eye Science
关键词
眼科手术
辅助镇痛
局部麻醉
ophthalmologic operation
relieve pain
nefopam
