摘要
目的:观察壮肾排毒胶囊延缓慢性肾功能衰竭(CRF)的临床疗效。方法:将80例患者随机分为两组,治疗组42例用壮肾排毒胶囊治疗,对照组38例用尿毒清颗粒治疗,主要观察两组血清肌酐(Scr)、尿素氮(BUN)、内生肌酐清除率(Ccr)和血清纤维连接蛋白(FN)、透明质酸(HA)、Ⅲ型前胶原(PC-Ⅲ)、Ⅳ型胶原(Col-Ⅳ)的改善情况。结果:治疗组有明显的降低慢性肾功能衰竭患者血清Scr、BUN、HA、PC-Ⅲ、Col-Ⅳ和提高Ccr的作用,两组比较有统计学意义(P<0.05)。结论:壮肾排毒胶囊能改善肾纤维化,延缓慢性肾衰竭的进程。
Objective ： To observe the clinical effect on chronic of renal failure postponed by Zhuangshen Paidu capsules, Method： 60 cases were randomly divided into two groups. 42 cases in the treatment group were treated by Zhuangshen Paidu granules and 38 cases in the control group treated by Niaoduqing granules. The improvement of seral creatinine, usea nitrogen, creatinine clearance rate, fibronectin, hyaluronic acid, type three precollagen and type four collogen were observed. Results： seral creatinine, usea nitrogen hyaluronic acid, type three precollagen and type four collogen were decreased significantly and creatinine clearance rate increased in the treatment group. It has statistical significance as compared with the control group （P 〈 0.05 ）. Conclusion： Zhuangshen Paidu capsules could improve renal fibrosis and postpone course of renal failure.
出处
《湖南中医杂志》
2008年第4期1-3,共3页
Hunan Journal of Traditional Chinese Medicine
