蒙古黄芪中药对提高间歇运动大鼠心肌组织抗自由基能力的研究

A Study on Astragalus Mongholicus Bunge Enhancing the Ability of Anti-Free Radical in Intermittent Training Rats'Myocardium Tissue

将60只雄性Wistar大鼠,随机分为6组,进行训练测试。测定不同组别心肌组织中超氧化物歧化酶(SOD)和过氧化氢酶(CAT)活性及丙二醛的含量。结果显示:运动训练后灌胃蒙古黄芪水煎剂能显著提高大鼠心肌组织中超氧化物歧化酶(SOD),并能显著降低丙二醛(MDA)的含量(p<0.01),但过氧化氢酶(CAT)的活性无显著性变化(p>0.05)。从而证实了蒙古黄芪中药是一种有效的自由基清除剂,可减轻运动后因脂质过氧化而产生的内源性自由基对机体的损伤,具有增强抗氧化酶活性和提高大鼠运动能力的作用。

To observe the effect of Astragals Mongholicus Bung （AMB） on free radicals metabolism, SOD, CAT, MDA after exhaustive swimming, The result shows that the content of SOD activity increases significandy （p〈0.01） and the content of MDA reduces significandy（p〈0.01） while the content of CAT activity increases no significandy （p 〉0.05） after exhaustive swimming. The result suggests that AMB is an effective antioxidant can decrease free radical and improve exercise endurance and anti-oxidative status in rats.