生长相关蛋白免疫反应神经纤维在大鼠垂体前叶的分布

Distribution of GAP-43 in the anterior pituitary of rat

生长相关蛋白（GAP－43）是神经生长再生的一种标志蛋白，研究大鼠垂体前叶GAP－43的阳性分布，为进一步研究垂体前叶内神经可塑性创造条件．方法：免疫组织化学ABC染色法（硫酸镍铵加强法）．结果：在大鼠垂体前叶有一定数量的GAP－43阳性神经纤维，其分布为周边较中央多，两侧较内侧部多．结论：垂体前叶内有GAP－43阳性神经纤维，表明其具有再生发芽的能力．

GAP-43 is a signal protein of nerve growth axonal regeneration. This experiment tells the distribution of GAP-43 immunoreactive nerve in the anterior pituitary of rat, in order to do something for the further research of the plasticity of the nerve fibers in the anterior pituitary. Method: Immunohistochemistry.Result: Substantial amounts of GAP-43 immunoreactive nerve fibers were visualized. The number of the fibers at the peripheral part is more, so is at the latteral portion of the pars distalis. Conclusion: The existance of GAP-43 immunoreactive nerve fibers in the anterior pituitary of rat suggests the ability of sprouting and regeneration of this peptidergic nerve fibers.