锌硒宝对轮状病毒性肠炎患者体液免疫功能的影响

Effect of Xinxibao on the humoral immunologic functions of patients with rotavirus enteritis

目的探讨锌硒宝对轮状病毒性肠炎患者体液免疫功能的影响。方法检测260例轮状病毒肠炎患者免疫球蛋白及补体，治疗组除常规治疗外，加用锌硒宝治疗，并观察两组患儿临床疗效及免疫功能变化。结果急性期患儿血清IgG、IgM、IgA、C3均明显降低，C4无明显改变，治疗组有效率（81．6％）明显高于对照组（63．5％），且治疗组IgG、IgM、IgA、C3较治疗前明显升高，C4变化不明显。结论轮状病毒肠炎患者存在免疫功能紊乱，锌硒宝有助于患儿缩短病程，增强恢复期患儿免疫功能。

Objective To discuss the effect of Xinxibao to rotavirus enteritis sufferers＇ humoral immunologic functions. Methods 260 cases rotavlrus enteritis sufferers＇ immunoglobulin and its alexin were measured. Except conventional therapy, the treatment group plus the Xinxibao to cure, and observe two sufferer teams＇ clinical curative effect and the change of immunologic function. Results The acute stage sufferers＇ blood serum IgG, IgM, IgA, C3 were lower obviously, C4 didn＇t have obvious change, the activity ratio of the treatment group（81.6 % ） is obviously higher than the control group（63.5 % ）. At the same time, the treatment group IgG, IgM, IgA, C3 rose obviously than before,C4 had no change. Conclusion The rotavirus enteritis sufferers＂ immunologic functions are disorder, Xinxibao is useful to shorten the treatment of the sufferers, and strengthen sufferers＂ immunologic functions in the restoration stage.