复方川脊片质量标准研究

Study on the Quality Standard for FufangChuanji Tablets

目的建立复方川脊片的质量标准。方法采用薄层色谱（TLC）法对处方中的狗脊、续断、伸筋草等3种药材进行定性鉴别;采用HPLC法测定复方川脊片中芍药苷的含量。结果在TLC色谱中均能检出狗脊、续断、伸筋草,复方川脊片中芍药苷与其它组分良好分离,芍药苷浓度线性范围在0.204 8-1.024μg,r=0.999 3,样品加样回收率为99.05%,RSD=1.13%（n=6）。结论所建立的方法简便可性,重复性好,可作为复方川脊片的质量控制方法。

Objective To establish a standard for the quality control of FufangChuanji Tablets. Methods Rhizome Cibotii, Radix Dipsaci and Herba Lycopodti were identified by TLC, and the content of paeoniae was determined by HPLC. Results There was a good linear relationship within a range of 0. 2048 - 1. 024 μg for Paeoniflorin , correlation coefficient r = 0.9993, the average recovery was 99.05% （n = 6）, RSD = 1.13%, （n = 6）. Conclusion This method is simple ,feasible and reproducible and can be used for quality control of FufangChuanji Tablets.