针刺外关穴和非穴SPECT脑功能成像的比较研究

A Comparative Study of SPECT Cerebral Functional Imaging on Needling in the Acupoint Waiguan(SJ5) and a Sham Acupoint

目的:运用SPECT脑功能成像技术,比较针刺外关穴、针刺非穴不同状态下,青年志愿者不同脑区的激活情况,以印证"经穴特异性-脑相关假说"。方法:18例健康志愿者,随机分为正常对照组、外关穴针刺组、非穴针刺组,分别接受不同的处理。同时,运用GE公司M illennium MG SPECT系统完成脑部扫描。所得图像采用SPM2软件包进行处理和分析。结果:与正常对照组比较,外关穴针刺后BA 3、2、20、46区、以及壳核、尾核、岛叶等区域有激活点;非穴针刺后BA10、18、19、30、21、9、8、6、22区等区域有激活点,激活区域都集中在左侧;外关穴针刺组与非穴针刺组比较则表明,BA10、9、8、18、19、21、22、30区、以及小脑扁桃体等区域有负激活点。结论:针刺对脑区血流状态有着肯定的影响;针刺外关穴与针刺非穴存在着一定的差异。

Objective： The effects of needling in Waiguan （SJ 5） and needling in a sham point in young healthy volunteers were observed by SPECT cerebral functional imaging in order to prove the hypothesis of ＂Acupoim - specific has close relationship with the brain＂ . Method ： Eighteen young healthy volunteers were divided into 3 groups randomly and received the differem timulations of non - procession, needling in SJ5 and needling in a sham poiont. In the mean time, GE Millennium MG SPECT was used to make a cerebral scan and the collected pictures were analyzed by SPM2. Results ： Compared with the non - procession group, needling in SJ5 could sig- nificantly activate the areas of BA 3, 2, 20, 46 and putamen, caudate body and insula, while needling in a sham point could significandy activate the areas of BA10, 18, 19, 30, 21, 9, 8, 6 and 22. The comparision of needling in SJ5 and the sham point showed there were some deactivated areas of BA10, 9, 8, 18, 19, 2, 22, 30 and cerebellar tonsil Conclusion： Needling has a positive effect on the regional cerebral blood flow and there is a difference between needling in the true point （SJ5） and the sham point proved by the deactive areas in the brain.