摘要
SLE好发于生育期女性，不可避免地会面临生育问题。近年来SLE女性患者妊娠已不视为禁忌。妊娠对SLE的病情会有影响，可诱发或加重SEE；相反，SLE也会影响妊娠的过程和结局，易发生流产、死胎、死产等胎儿丢失情况及胎儿生长受限，也可发生新生儿红斑狼疮。了解可能影响妊娠及胎儿的免疫学变化和激素水平变化，掌握SLE患者的妊娠指征，合理用免疫抑制剂及正确的护理，在控制SLE活动的基础上，使患者分娩正常的胎儿，是临床医师面临的重要课题。
Systemic lupus erythematosus （SLE）predilects in women in child-bearing period, who unavoidably face problems of procreation. Nowadays, pregnancy is no longer looked as contraindication in SLE patients. Pregnancy may induce or even aggravate SLE, and SLE could affect the process and outcome of pregnancy, even lead to abortion, fetal death, stillbirth, fetal growth restriction or induce the development of neonatal lupus erythematosus （ NLE ）. So it is important for clinicians to learn the changes in immunology and hormone levels in women with SLE that may contribute to pregnancy and fetus, to be knowledgeable about the indication for SLE patients to be pregnant, to apply effective immunosuppressants and right care, and to control patients＇ condition so as to ensure normal pregnancy and childbirth.
出处
《国际皮肤性病学杂志》
2008年第4期221-223,共3页
International Journal of Dermatology and Venereology
关键词
红斑狼疮
系统性
妊娠
免疫抑制剂
Lupus erythematosus, systemic
Pregnancy
Immunosuppressive agents
