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OSEM重建算法中几个关键问题的研究 被引量:2

Research on Some Key Problems in the OSEM Algorithm
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摘要 目的:改进平行孔准直器SPECT系统的成像方法,快速、精确地实现有序子集期望值最大化(OSEM)重建算法。方法:采用理想平行孔和张角效应平行孔准直器两种模型,将准直器的空间响应融入系统传输矩阵,利用改进的射线跟踪算法进行衰减校正。结果:随着准直器张角的增加,Jaszczak模型的重建图像在边界出现明显的亮环;利用考虑准直器空间响应的系统矩阵进行图像重建,能较好的抑制边界伪影。结论:融入准直器空间响应函数的系统矩阵更为精确、贴近真实情况,能较好的抑制边界伪影,提高了重建图像的对比度和信噪比。 Objective: To improve a reconstruction method of the parallel-hole SPECT system, fast and accurately realize the OSEM algorithm. Methods: By using a perfect parallel-hole collimator model and a collimator model considering the splayed angle effect, this paper proposed a novel method which considers the space response function (SRF) calculating the system matrix and uses an improved Ray Tracing algorithm to perform attenuation correction. Results: The Jaszczak phantom's edge overshoot artifact will appear and will more evidence with the increasing of angle the collimator splayed, but using the system matrix calculated from the novel method the edge artifact can be eliminated. Conclusion: After considering the SRF, the system matrix is more accurate, and the reconstruction image's contrast and SNR are improved.
出处 《中国医学物理学杂志》 CSCD 2008年第4期729-736,共8页 Chinese Journal of Medical Physics
基金 科技部973项目(2006CB70570005) 北京滨松光子技术股份有限公司合作项目(147018)
关键词 OSEM 平行孔准直器 张角效应 准直器空间响应函数 边界伪影 OSEM parallel-hole collimator splayed angle effect space response function edge artifact
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同被引文献23

  • 1高平,秦绍森,蔡晓杰,刘银红,韩丽君,于治国.Alzheimer病与轻度认知功能障碍的脑SPECT显像[J].中华核医学杂志,2006,26(4):213-215. 被引量:9
  • 2张春银,李作孝,陈跃,谭华,李晓红.脑出血患者缺血性脑损害局部脑血流灌注的SPECT显像[J].中华核医学杂志,2006,26(5):290-292. 被引量:3
  • 3尤江生,包尚联,蔡建新,王卫东.SPECT准直器几何及图像重建算法的进展[J].核电子学与探测技术,1997,17(3):221-224. 被引量:1
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  • 5Nagasawa N,Yamakado K,Yamada T,et al.Three-dimentional stereotactic ROI template for measuring regional cerebral blood flow in ^99Tc^m-ECD SPECT:comparison with the manual tracing method.Nucl Med Commun,2009,30:155-159.
  • 6Koch W,Hamnn C,Welsch J,et al.Is iterative reconstruction an alternative to filtered backprojection in routine processing of dopamine transporter SPECT studies? J Nucl Med,2005,46:1804-1811.
  • 7Biersack HJ,Freeman LM.Clinical Nuclear Medicine.New York:Springer,2007:8-23.
  • 8Accorsi R.Brain single-photon emission CT physics principles.Am J Neuroadiol,2008,29:1247-1256.
  • 9Bruyant PP.Analytic and iterative reconstruction algorithms in SPECT.J Nucl Med,2002,43:1343-1358.
  • 10尹大一,陈英茂,姚树林,邵明哲,尹岭,崔红燕,田嘉禾.图像重建条件对PET脑显像SPM分析结果的影响[J].中华核医学杂志,2007,27(5):303-305. 被引量:2

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