摘要
目的探讨外阴阴道念珠菌病(Vulvovaginal candidiasis,VVC)相关危险因素。方法采用前瞻l生研究方法,对230例阴道内念珠菌培养阳性者及200例培养阴性者进行病例对照研究。结果VVC主要发生于性活跃期育龄妇女,平均年龄为(31.01±8.43)岁。VVC的相关危险因素有口交、非月经期护垫的应用、口服避孕药、既往有VVC病史、抗生素应用(OR分别为5.85,12.05,6.46,1.41,4.07;95%C1分别为2.82—12.13,5.38—26.97,3.51—11.98,0.71—2.78,1.35—12.26);避孕套的应用是保护性因素(OR=0.67,95%CI0.57—0.78)。结论VVC主要发生于性活跃期育龄妇女,口交、非月经期护垫的应用、避孕药的应用、既往有VVC病史、抗生素的应用是VVC发生的高危因素。避孕套的应用是VVC的保护性因素。
Objective To evaluate the risk factors in vulvovaginal candidiasis. Methods The present study was designed as an case controlled study using prospective study methods. Patients were divided into two groups: 230 patients with positive-culture for candidias was case group. Control group consist of 200 patients whose cuhure for candidias were negative. Results The mean prevelence age was 31.01 ± 8.43. The following factors were associated with VVC: Oral sexual habits, panty liners used , VVC history , oral contraception, antibiotic use ( OR = 5.85,12. 05, 6.46, 1.41,4.07, 95% CI 2. 82-12. 13, 5.38-26. 97, 3.51-11.98,0.71- 2. 78, 1.35-12.26, respectively), Condom use was a protective factor ( OR = 0. 67,95 % CI 0.57-0.78 ). Concluslon The highest prevalence of vulvovaginal candidasis was found in birth-age women. Oral sexual habits, Panty liners used during menstruation, VVC history , Oral contraception , Antibiotic use , all above were risk factors associated with VVC. Condom use was a protective factor.
出处
《中国实用医药》
2008年第20期17-18,共2页
China Practical Medicine
关键词
外阴阴道念珠菌病
危险因素
念珠菌
Vulvovaginal candidiasis
Clinical features
Risk factor
Candida