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多西紫杉醇联合表柔比星治疗晚期乳腺癌的临床观察 被引量:3

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摘要 目的观察多西紫杉醇联合表柔比星治疗晚期乳腺癌的疗效与不良反应。方法表柔比星100mg/m2第1天,多西紫杉醇75mg/m2第1天,应用的前1d和当天给予相关的抗过敏治疗,化疗过程中常规给予格拉斯琼止吐及其他对症治疗,28d为1个周期。全组病例化疗中位周期数为3.3个周期(平均2~6个周期)。结果全组有效率为(CR+PR)为53.57%,以淋巴结与骨转移疗效较高,肝肺转移疗效较差。主要不良反应为消化道反应、血细胞减少、脱发。绪论多西紫杉醇联合表柔比星化疗方案治疗晚期乳腺癌疗效高、毒副反应容易防治并可以耐受,可以作为晚期乳腺癌患者的一线化疗方案,同时也可以作为复治晚期乳腺癌的解救方案。
出处 《中国基层医药》 CAS 2008年第5期802-803,共2页 Chinese Journal of Primary Medicine and Pharmacy
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