影响肝脏螺旋CT增强强化效果相关因素分析

Factors influencing the effect on contrast enhancement during spiral CT of the liver

目的探讨性别、年龄、体重、对比剂剂量及注射速度等因素对肝脏螺旋CT增强强化效果的影响。方法106例肝脏螺旋CT增强患者，对比剂剂量为80～90ml，注射速度2．5～4ml，开始注射对比剂后25S从肝顶叶按1cm／s速度行肝脏双期扫描，分别测量每个患者的体重、腹主动脉动脉期腹腔干层面CT值和门脉期同一层面门静脉及肝实质CT值。结果患者体重与腹主动脉强化密度存在负性相关（P〈0．05），年龄、注射速度等与腹主动脉强化密度成正性相关（P〈0．05）；门脉期肝实质强化密度与动脉期主动脉及门脉期门静脉存在线性相关（P〈0．05）。结论肝脏螺旋CT强化密度随着年龄及注射速度增高而增强，随着体重增加强化密度降低。

Objective To investigate the factors influencing the effect of contrast-enhanced density of liver with spiral CT. Methods CT values were measured at the aorta on arterial phase, and at the portal vein and hepatic parenchyma on portal phase fixed at the same level. Results The enhancement density of the aorta was negatively linearly correlated with body weight （P〈0. 05） and positively with age and delivery rate on arterial phase （P〈0. 05）. Enhancement density of the hepatic parenchyma was linearly correlated with the portal vein and the aorta （P〈0. 05）. Conclusion The enhancement density of liver increases with the age and delivery rate rise, but decreases with the increasing of body weight. The contrast medium dose and rate should be determined based on the age and the body weight.