心血管可降解金属材料的研究进展

Research progress in biodegradability metal for cardiovascular stent

着重介绍了治疗心血管疾病中开发、研究金属类可降解材料的重要性,通过国内外研究可降解心血管材料所出现的问题进行了综述,特别对镁和纯铁的理化性质、生物相容性、耐腐蚀性能进行了比较和分析,论证了研制可降解金属材料的可能性。研究证明:对医用金属表面进行气体注入或稀土金属注入能在一定程度上提高金属在体内的抗蚀能力,通过合理的注入工艺和控制注入离子在金属中的分布密度、存在状态、注入深度,将可能有效的控制金属离子释放速率,这为研究和开发可降解心血管金属材料提供一条有效途径。

The essentiality of developing and researching biodegradability metal for cardiovascular stent was emphasized in this paper. The present issue was stated in investigating biodegradability cardiovascular stent, including compare and a nalysis physical chemistry property, biocompatibility and resistant corrosion character for magnesium and pure iron, gradually the probability of developing biodegradability metal was argued. It was proved that the property on resistant corrosion of metal were enhanced considerably when gas or rare earth metal was implanted into surface of metal, the factors influence ion distributing density, exit estate and implantion depth were implantion technics and variety ions, above all effect degradable velocity possibly. It was available approach to develop biodegradability metal for cardiovascular stent evidently.