经皮氧分压测定在糖尿病足中的临床应用

Clinical use of transcutaneous oxygen pressure measurement in diabetic foot

糖尿病足是糖尿病严重的慢性并发症,而下肢皮肤微循环功能障碍致皮肤氧供应减少是糖尿病足的重要危险因素。目前临床常用的检测下肢血管病变的方法均未能很好反映糖尿病足局部微循环情况,而经皮氧分压测定可以直接反映微循环的功能状态,可早期发现糖尿病足溃疡风险,预测溃疡愈合可能,选择截肢平面,监测病情变化,评价治疗效果,为糖尿病足的诊治提供有价值的信息。

Diabetic foot is the severe chronic complication of diabetes mellitus. The impairment of the topographic skin microcirculation decreases the skin oxygenation of the lower limb, and plays an important role in the development of the diabetic foot. Transcutaneous oxygen pressure（TcPO2） is a noninvasive method reflecting topographic skin microcirculation directly and can be used to detect diabetic patients at risk of foot ulceration and predict the healing of foot ulcers . TcPO2 tension also seems to be useful for determining the optimal amputation level, monitoring clinical progression and evaluating the therapeutic efficacy. Measurement of transcutaneous oxygen pressure provides valuable information for diabetic foot.