超声在出生缺陷产前诊断中的临床应用

Clinical implication of prenatal ultrasonography for detecting birth defects

目的 探讨超声在产前诊断胎儿缺陷的临床价值。方法 对4927例孕16～40周的妇女采用实时彩色多普勒超声仪进行系统检查，对胎儿畸形进行筛查和诊断。结果 在4927例孕妇中，共发现先天性缺陷58例，产前共诊断出48例胎儿畸形，漏诊10例。漏诊病例主要表现为较小畸形和缺陷。结论 妊娠中晚期进行系统超声检查可以对胎儿形态结构方面的明显畸形进行产前诊断，对于降低出生缺陷发生率，提高人口素质具有重要意义。

Objective： To explore the clinical significance of prenatal uhrasonography for detecting birth defects. Methods： A total of 4927 women during 16 -40 gestational weeks under went real -time color Doppler ultrasonography to find out fetal congenital anomalies. Results： In all 4927 pregnant women, 58 cases were diagnosed fetal congenital anomalies on ultrasonography, Another 10 cases who had micro - malformation were misdiagnosed on color Doppler ultrasonography. Conclusion ： A systemic prenatal ultrasonographic examination in the second - trimester pregnancy is important for prenatal diagnosis of congenital malformations, which plays very significant role in decreasing fetal birth defects and improving new born population quality.