肾上腺肿瘤62例临床病理分析

Clinical and pathological analysis of 62 cases of adrenal masses

目的分析肾上腺肿瘤的临床病理学特征。方法对1991～2003年62例肾上腺肿瘤的临床病例资料进行分析。患者经B超检查发现肿瘤,并经手术切除,然后将肿瘤送病理学检查。结果在62例肾上腺肿瘤中,男25例,女37例,平均38.5岁。病理诊断为肾上腺皮质腺瘤18例、腺癌3例,嗜铬细胞瘤2 l例,其中15例为隐匿性肿瘤（意外瘤）。结论肾上腺肿瘤以皮质腺瘤和髓质嗜铬细胞瘤为主,以良性者多见,但良恶性鉴别困难。对肾上腺肿瘤的诊断应当将影像学定位与病理学定性结合起来,明确肿瘤类型,对于直径大于3 cm者尽早采用手术治疗。

Objective To analyze the clinical and pathological characteristics of the adrenal masses. Methods Sixty-two patients with adrenal masses from 1991 to 2003 were collected and analyzed. The masses were detected by ultrasound scan. All patients were treated by surgical removal of the masses which were later further underwent pathological study. Results In the 62 patients studied, there were 25 men and 37 women with the average age of 38. 5. Pathological study revealed that the tumors were found to be adrenal cortical adenomas （ 18 cases ） , adenocareinoma （ 3cases ） , pheochromacytomas （ 21 cases ）. Fifteen cases of the masses were incidentalomas. Conclusion Among adrenal tumors, the common types are adrenal cortical adenomas and pheochromacytomas. Many of the tumors are benign which are difficult to be distinguished from the malignancies. The diagnosis should be made based on the combination of imaging with pathology. Those with a diameter over 3 cm need removol surgically as soon as possible.