白细胞及血红蛋白对急性主动脉夹层近期预后的预测价值

The prognostic value of white blood cell and hemoglobin in patients with acute aortic dissection

目的评价外周血白细胞总数及血红蛋白水平对急性主动脉夹层（AAD）近期预后的预测价值。方法测定42例AAD患者入院时白细胞总数、血红蛋白及纤维蛋白原水平，并观察住院期间其病死率，对AAD患者近期预后进行分析评价。结果住院期间死亡13例（死亡组），病死率为30．95％。死亡组白细胞总数显著高于存活组，分别为（13、73±6．91）×10^9／L和（9．43±4．97）×10^9／L（P〈0.05）；死亡组血红蛋白水平显著低于存活组，分别为（118．54±22．38）g/L和（131．72±18．17）g/L（P〈0、05）；死亡组与存活组纤维蛋白原水平差异无统计学意义，分别为（3．15±1、15）g/L和（3、48±1．24）g/L（P〉0．05）。白细胞总数升高组（≥10．0×10^9／L）病死率显著高于白细胞总数正常组（〈10、0×10^9／L），分别为41、18％和24、00％（P〈0．05）。血红蛋白水平减低组（≤110g/L）病死率显著高于血红蛋白水平正常组（〉110g/L），分别为50．00％和27．78％（P〈0.05）。结论白细胞总数及血红蛋白水平有助于判断AAD的近期预后。

Objective To evaluate the prognostic value of white blood cell and hemoglobin in patients with acute aortic dissection （ AAD ）. Methods White blood cell, hemoglobin and fibrinogen were measured in 42 AAD patients. The mortality during hospitalization was observed and the short-term prognosis in AAD patients was assessed. Results There was 13 death during hospitalization, with the mortality of 30.95%. The value of white blood cell was higher in death group than in survival group [ （ 13.73±6.91 ） ×10^9/L vs. （ 9.43±4.97 ）× 10^9/L ,P 〈 0.05 ）. The value of hemoglobin was lower in death group of than in survival group [ （ 117. 54 ± 22.38 ） g/L vs. （ 131.72 ± 18. 17 ） g/L, P 〈 0.05 ]. There were no differences in the value of fibrinogen between the groups [ （ 3.15 ± 1.15 ） g/L vs. （ 3.48 ± 1.24 ） g/L,P 〉 0.05 ）. The mortality in the group of elevated white blood cell（ ≥ 10.0 × 10^9/L）was higher than that in the group of normal white blood cell（ 〈 10.0 × 10^9/L） （41.18% vs. 24% , P 〈 0.05 ）. The mortality in the group of decreased hemoglobin（ ≤ 110 g/L ） was higher than that in the group of normal hemoglobin （ 〉 110 g/L ） （ 50.00 % vs. 27.78 % , P 〈 0.05 ）. Conclusion The value of white blood cell and hemoglobin could help to assess the short-term prognosis of patients with AAD.