氮氧化钛涂层支架在冠状动脉血运重建中的初步应用

Initial use of trans-ulner or trans-radial approach to coronary revascularization with titanium-nitride-oxidecoated stent

目的探讨氮氧化钛涂层（TITAN2）支架在经彬尺动脉途径行冠状动脉血运重建的临床效果。方法入选31例冠心病患者，均采用经桡动脉或尺动脉途径行冠状动脉血运重建。计算TITAN2支架病变的通过率、早期支架内血栓发生率及随访MACE发生率。结果31例冠状动脉造影发现46处〉75％狭窄病变，植入支架45枚，1枚支架未能通过病变，通过率97．8％。植入支架后无残余狭窄、支架脱载、内膜撕裂、支架内早期血栓形成及冠状动脉破裂。随访1～5个月，无MACE发生。结论TITAN2支架在冠状动脉血运重建方面临床应用效果良好。

Objective To evaluate the efficacy of trans-ulner or trans-radial approach to coronary revascularization with titanium-nitride-oxide-coated stent （ TITAN2 ）. Methods 31 patients, who were planed to receive coronary revascularization,were selected into this study. All patients with coronary revascularization were either by trans-ulner or by trans-radial approach. The pass-through rate of stent, early thrombosis in stent and MACE at followup were recorded for TITAN2. Results 46 lesions with stenosis 〉 75% with coronary angiography in 31 patients successfully underwent coronary revascularization with TITAN2. One stent didn＇t go through the lesion in RCA. The pass-through rate of stent was 97.8%. Remaining stenosis, stent unglues, endarterium laceration, early thrombosis in stent and coronary rupture were not discovered after stent deployment. MACE was 0 at 1-5 month follow-up. Conclusion Confirmed good efficacy in coronary revascularization with TITAN2 is observed.