摘要
目的观察国产吉西他滨联合草酸铂(GEMOX)方案治疗老年非小细胞肺癌的疗效及毒副反应。方法对26例年龄在65~75岁之间的晚期非小细胞肺癌(NSCLC)患者施以国产吉西他滨(泽菲,GEM)1000mg·m^-2静脉滴注d1,d8;草酸铂(LOHP)100mg·m^-1。静脉滴注d1。结果总有效率为42.3%(11/26),中位生存期8.9个月,一年生存率39.3%。结论国产吉西他滨联合草酸铂治疗老年晚期NSCLC不仅疗效好,而且毒副反应轻,治疗耐受性好,是老年晚期NSCLC患者理想的化疗方案,值得应用和推广。
Aim To observe the therapeutic effect and side effects of homemade Gemeitabine associated with Oxaliplatin in aged patients with late nonsmall-cell lung cancer, Method 26 aged patients between 65 and 75 years old with late nonsmall-cell lung cancer were treated with homemade Gemeitabine at 1 000 mg · m^-2 on the day 1st and the day 8th associated with Oxaliplatin at 100 mg · m^-2 on the day 1 st through intravenous drip, Result The total effective rate is 42. 3% ( 11/26), eight to nine months of Median Survival Time and 39.3% of survival rate. Conclusion There is a better therapeutic effect with slight and endurable side effects of homemade Gemcitabine associated with Oxaliplatin in aged patients with late nonsmall-eell lung cancer, which is worth applying and advertising for the clinic use.
出处
《安徽医药》
CAS
2008年第8期739-740,共2页
Anhui Medical and Pharmaceutical Journal
关键词
国产吉西他滨
草酸铂
老年
非小细胞肺癌
homemade Gemcitabine
Oxaliplatin
aged
nonsmall-eell lung cancer