叶瓜参中的三个海参皂苷

Three Tritserpene Glycosides from Sea Cucumber Cucumaria frondosa Gunnerus

目的:研究叶瓜参体内的化学成分,寻找结构新颖的三萜皂苷类化合物。方法:应用多种色谱技术对叶瓜参体内的化学成分进行分离纯化,根据化合物的理化性质和波谱数据鉴定其结构。结果:分离得到三个三萜皂苷化合物,分别为frondoside A6(1),frondoside A(2)和frondoside A1(3)。结论:化合物1为一个新的三萜皂苷。

AIM： To study the constituents of sea cucumber Cucumariafrondosa Gunnerus. METHODS： Triterpene glycosides from Cucumariafrondosa Gunnerus were separated and purified by silica gel chromatography, reversed-phase silica gel chromatography and reversed-phase HPLC. RESULTS： Their structures were elucidated as frondoside A6（1）, frondoside A（2） and frondoside A1 （3） on the basis of chemical evidence and spectral data. CONCLUSION： Frondoside A6 （1） is a new triterpene glycoside.