毛鱼藤根中的异黄酮类成分及其衍生物

Isoflavones and Their Derivatives from the Root of Derris elliptica (Roxb.) Benth.

目的:对广东产毛鱼藤(Derris elliptica(Roxb.)Benth.)根的化学成分进行研究。方法:运用多种层析手段进行分离纯化,通过波谱解析和理化鉴别进行结构鉴定。结果:分离鉴定了8个异黄酮类化合物,分别为:樱黄素(prunetin,1),芒柄花素(formononetin 2),pseudoboptigen(3),3′-methoxydaidzein(4),染料木素(genistein 5),大豆素(daidzein 6),dihydrodaidzein(7),demethylvestitol(8)。结论:化合物1,2,5,6为首次从毛鱼藤中分得,化合物3,4,7,8为首次从鱼藤属中分得。

AIM： To study the chemical constituents of Derris elliptica （Roxb.） Benth. METHODS ：The chemical constituents were isolated by various chromatographic methods, and the chemical structures were elucidated on the basis of spectral analysis. RESULTS： Eight isoflavones were obtained and their structures were identified as prunetin （1）, formononetin （2）, pseudoboptigen （3）, 3′-methoxydaidzein （4）, genistein （5）, daidzein （6）, dihydrodaidzein （7）, demethylvestitol （8） CONCLUSION： Compounds 1, 2, 5, 6 were isolated from Derris elliptica （Roxb.） Benth. for the first time and compounds 3, 4, 7, 8 were isolated from the genus for the first time.