酸枣仁的化学成分

Chemical Constituents from the Seeds of Ziziphus jujuba var.spinosa

目的:对酸枣仁化学成分进行分离和鉴定。方法:运用硅胶、ODS、Sephadex LH-20柱层析和重结晶等方法分离纯化,根据理化性质和波谱方法鉴定结构。结果:从酸枣仁中分离得到8个化合物,分别鉴定为羽扇豆醇(1),白桦脂酸甲酯(2),豆甾-4-烯-3-酮(3),过氧麦角甾醇(4),菜油甾醇(5),异当药黄素(6),甘油(7)和pseudolaroside B(8)。结论:化合物1-8均为首次从该植物中分离得到。

AIM： To study the chemical constituents from the seeds ofZiziphusjujuba var. spinosa. METHODS： The constituents were isolated and purified by silica gel, ODS and Sephadex LH-20 column chromatographic methods as well as recrystaltization. The chemical structures were elucidated on the basis of physicochemical properties and spectral data. RESULTS： Eight compounds were isolated and identified as lupeol （1）, methyl betulinate （2）, stigmast-4-en-3-one （3）, 5a,8a-epidioxy-（22E,4R）-ergosta-6,22-dien-3fl-ol （4）, campesterol （5）, isoswertisin （6）, glycerol （7） and pseudolaroside B （8）. CONCLUSION： Compounds 1-8 were isolated from this plant for the first time.