马来酸桂哌齐特治疗急性脑梗死的临床疗效观察

Effect of Cinepazide Maleate Injection in treatment of patients with acute cerebral infarction

目的观察马来酸桂哌齐特治疗急性脑梗死(ACI)的临床疗效。方法将84例ACI患者随机分为治疗组和对照组各42例,分别给予马来酸桂哌齐特注射液和复方丹参注射液治疗。结果①治疗组的神经功能改善程度明显优于对照组(P<0.05);②治疗组生活能力的改善程度也显著优于对照组(P<0.01);③治疗组的显效率为54.8%,对照组的显效率为28.6%,两者比较差异有显著性(P<0.05);治疗组的总有效率(83.3%)也显著高于对照组(61.9%),P<0.05,且未见明显副作用。结论马来酸桂哌齐特能有效改善ACI患者的神经功能和生活能力。

Objective To observe the elinical effect of Cinepazide Maleate Injection in treatment of patients with acute cerebral infarction （ACI）. Methods 84 ACI cases were divided randomly into treatment group and control group, receiving treatment of Cinepazide Maleate Injection and Fufang Danshen Injection respectively.Results ①There were significant differences in nervous functional defeet scale after treatment between two group, the treatment group was obviously lower than control group（P〈0.05）.②There were significant differences in living ability after treatment between two group, the treatment group was obviously lower than control group too （P〈0.01）. ③The improving rate of treatment group was significantly higher than that of control group （54.8% vs 28.6%. P〈0.05）.The total effectiveness rate of treatment group was significantly higher than that of control group （83.3% vs 61.9%, P〈0.05） too, and treatment group had few side effects occurred.Conclusion Cinepazide Maleate can effectively improve the nervous function and living ability of cases with ACI.