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D-二聚体与冠状动脉病变关系的探讨

A study on the correlation between plasma D-dimer and coronary artery disease
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摘要 目的探讨冠状动脉硬化性心脏病(冠心病)患者血浆D-二聚体水平与冠状动脉病变程度的关系。方法测定145例行冠状动脉造影病例的D-二聚体水平。根据冠状动脉造影结果分为冠脉造影阴性组和冠脉造影阳性组,冠脉造影阳性组又分为单支病变组和多支病变组,比较各组间D-二聚体水平。结果冠脉造影阳性组D-二聚体水平显著高于冠脉造影阴性组(P<0.05),冠脉造影阳性组中冠脉多支病变组D-二聚体水平明显高于冠脉单支病变组(P<0.05)。结论血浆D-二聚体水平与冠脉病变程度密切相关,能在一定程度上反映冠脉病变程度和指导临床治疗。 Objective To investigate the correlation between coronary artery disease and plasma D-dimer .Methods Plasma D-dimer was measured in 145 patients being undergone coronary angiography .According to the results of CAG,the patients were divided into negative group ,and positive group including single vessel group and multiple vessel group.Results The levels of D-dimer in positive group were higher than that of negative group (P〈0.05) .D-dimer level in multiple vessel group was higher compared with that of single vessel group ( P〈0.05).Conclusion The levels of D-dimer closely related to coronary artery disease.The range of coronary disease was influenced by D-dimer and it can guide the clinic therapy.
出处 《中国现代医药杂志》 2008年第7期56-57,共2页 Modern Medicine Journal of China
关键词 D-二聚体 冠脉病变 临床分析 治疗方法 D-dimer Coronary artery disease
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