摘要
目的:评价杏丁注射液治疗不稳定型心绞痛的临床疗效及安全性。方法:对照组为常规治疗组,即根据病情常规选用抗血小板药物、抗凝药物、β受体阻滞剂、钙拮抗剂或硝酸类药物等;杏丁组为在常规治疗的基础上加用杏丁注射液,用法为20ml杏丁注射液加入5%葡萄糖溶液或生理盐水中静脉滴注,1次/d,2周为1疗程。结果:杏丁组治疗后心绞痛缓解和心电图改善情况明显优于对照组(P<0.05),杏丁组在治疗后平均心肌缺血总时间明显减少而平均心肌缺血减少时间明显增加(P<0.01),在降低血黏度及血小板聚集率方面,杏丁组明显优于对照组(P<0.01或P<0.05)。结论:杏丁注射液治疗不稳定型心绞痛疗效确切、安全,副作用少,值得临床推广应用。
Objective: To evaluate the efficacy and safety of Xingding injection in the treatment of unstable angina pectoris. Methods: The control group for the conventional treatment group was treated with traditional drugs, such as anti-platelet, antoc oaguiant, beta blockers,calcium antagonists or nitrates;the Xingding group was treated with traditional drugs as well as Xingding injections(20ml in 5% glucose solution or NS, inreavenous drip, once a day for two weeks). Results: The situation of angina mitigation and ECG improve in the Xingding group is much better than the control group (P〈0.05), The average total time of myocardial ischemia decreased significantly in Xingding group,while the average reducing time of myocardial ischemia increased significantly(P〈 0.01). The situation of reducing blood viscosity and platelet aggregation in Xingding group is much better than that in control group(P〈0.01 or P〈0.05). Conclusion:Xingding injection is an effective and safe drug for the treatment of unstable angina pectofis. It can be widely used clinically.
出处
《赣南医学院学报》
2008年第3期342-344,共3页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
关键词
杏丁注射液
不稳定型心绞痛
Xingding injection
unstable angina pectoris
clinical evaluation