多途径动脉灌注化疗及栓塞治疗对伴发远处转移的晚期妇科恶性肿瘤疗效初步分析

Preliminary analysis on the effectiveness in the treatment of advanced gynecologic carcinomas with distant metastases using the selective infusion of anticancerous agents and embolus by ways of artery intubation

目的：探讨多途径动脉灌注化疗及栓塞治疗对已有远处脏器转移的妇科恶性肿瘤的效果。方法：对有肝、肺脏转移的晚期恶性肿瘤２９例进行了选择性盆腔动脉、肝动脉和肺动脉插管造影，继行化疗及栓塞治疗。结果：经治疗１５～３０ｄ后，２１例（７２．４％）病灶直径缩小５０％以上，５例（１７．２％）病灶直径缩小不足５０％，３例（１０．４％）治疗效果不明显。结论：多途径动脉灌注造影，行药物及栓塞治疗对有远处脏器转移的晚期恶性肿瘤有一定疗效，不仅有较强的局部作用，而且副作用较轻。但本组例数较少，随诊时间短，有关问题有待进一步研究。

Objective:To investigate the effect of treatment in advanced gynecological carcinomas with lung or/and liver metastases using selective infusion of anticancerous agents and embolus by ways of arterial intubation.Methods:Twentynine patients with advanced gynecological carcinomas with liver,lung metastases proved by clinical and pathology were treated by the infusive chemotherapy and embolus through selective arterial intubation.Results:After treatment for 15 to 30 days with above mentioned therapeutic methods,the diameters of cancer masses of twenty one patients(72.4%) became obviously smaller,five cases(17.2%) showed that their metastatic focuses became smaller,the rest three patients(10.4%)were not effected.Conclusions:The methods of the selective arterial infusion of anticancerous agents and embolus have clearly effected in the most patients with advanced gynecological carcinomas with distant metastases,and can provide an opportunity for radical operation.However,further investigation needs to be achieved for more cliniopathological examinations and long term followup.