用CDBFI技术检测恶性妊娠性滋养细胞肿瘤的子宫动脉血流阻力指数

Blood flow resistance index of uterine artery in patients with malignant gestational trophoblastic tumors examined by CDBFI

目的：探讨恶性妊娠性滋养细胞肿瘤（ＭＧＴＴ）患者的子宫动脉血液动力学变化。方法：采用彩色多普勒血流显像（ＣＤＢＦＩ）技术测定了正常妇女２０例和ＭＧＴＴ３０例化疗前、后的子宫动脉血流阻力指数（ＲＩ）值。结果：化疗前ＭＧＴＴ组的子宫动脉ＲＩ值较正常组低（Ｐ＜０．０１），显示了ＭＧＴＴ子宫血流低阻特性；化疗有效者，经≥３个疗程化疗后子宫动脉ＲＩ值较化疗前明显增高（Ｐ＜０．０５）。结论：用ＣＤＢＦＩ技术检测子宫动脉血流参数有助于ＭＧＴＴ的诊断及观察化疗疗效。

Objective:To assess the hemodynamics of the uterine arteries in patients with malignant gestational trophoblastic tumors.Methods:Using color Doppler blood flow imaging(CDBFI),the resistance index(RI) of the uterine arteries in 30 women with malignant gestational trophoblastic tumors was measured before and after each course of chemotherapy(examinated group).20 nonpregnant healthy women were used as controlled group.Results:The mean RI value of the uterine arteries in pretreatment of malignant gestational trophoblastic tumors was lower than that of controlled group(P<0.01).There was a marked increase of the mean RI value after the first three courses of chemotherapy in patients with good response to chemotherapy.Conclusion:CDBFI is a useful method in evaluating malignant gestational trophoblastic tumors and in monitoring the tumor response to chemotherapy.