三苯基膦-氯化钌-DPEN催化取代苯乙酮不对称加氢

RuCl_2[P(C_6H_5)_3]_2-(R,R)-DPEN a Novel Catalyst for Asymmetric Hydrogenation of Aromatic Ketones

用三苯基膦-氯化钌-DPEN配合物作催化剂催化了苯乙酮和几种邻位取代苯乙酮的不对称氢化反应。结果表明：此配合物对苯乙酮和几种邻位取代苯乙酮进行不对称氢化反应具有良好的催化性能和较高的对映选择性，在优化的条件下，其不对称氢化反应的转化率可达到100％，其ee值可达到49％～78％。

A ruthenium complex with DPEN and TPP as ligands was applied into the asymmetric hydrogenation of aromatic ketones. In optimized conditions, the reduction of Acetonaphthanone gave 100% conversation and 49%- 78% ee value.