磁共振扩散加权成像在肝脏疾病诊断中应用价值

Application of MRI diffusion weighted imaging on the diagnosis of hepatic lesions

目的分析肝脏常见良恶性病变磁共振扩散加权成像(DWI)影像特点,探讨表观扩散系数ADC值在肝脏占位性病变的价值。方法对肝正常25例及94例肝脏占位性病变患者进行扩散加权成像,并测量ADC值。结果在扩散敏感系数(b值)为600s/mm2的DWI上,正常肝组织ADC值为(1.52±0.24)×10-3mm2/s。肝囊肿、肝血管瘤、肝细胞癌、肝转移瘤ADC值分别为(4.04±0.64)×10-3mm2/s、(2.57±0.47)×10-3mm2/s、(1.43±0.51)×10-3mm2/s、(1.76±0.76)×10-3mm2/s,肝脏恶性肿瘤与肝囊肿、肝血管瘤均存在统计学意义(p<0.01)。结论分析扩散加权成像及测量ADC值对肝脏占位性病变诊断及鉴别诊断有一定价值。

Objective To study the characteristics of MRI diffusion weighted imaging （DWI） and apparent diffusion coefficient （ADC） measurement on the diagnosis of hepatic mass lesion. Methods Date of MRI DWI and ADC were obtained in 25 cases with normal subjects and 94 cases with hepatic mass lesions.ADC values were surveyed. Results OnDWl（（b = 600s/mm^2）, ADC valueswere （1.52±0.24）×10^-3 mm^2/s, （ 4. 04±0. 64 ）×10^-3 mm^2/s, （ 2. 57± 0. 47 ）×10^-3 mm^2/s, （ 1.43 ±0. 51 ）×10^-3 mm^2/s, （ 1. 76 ± 0.76 ）×10^-3 mm^2/s for normal liver,hepatic cyst, hepatic hemangioma, hepatic cancer and metastasis respectively. An obvious difference was showed between hepatic malignances and hepatic cyst and hemangioma （ p 〈 0.01 ）. Conclusion It is of significance on the diagnosis and differential diagnosis of hepatic mass lesions by analysing DWI and ADC value.