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肝癌组织中Livin蛋白的表达及其与临床病理特征的关系 被引量:7

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摘要 目的探讨Livin蛋白在肝癌组织中的表达及其意义。方法采用免疫组化SP法检测78例肝癌及33例肝血管瘤旁正常肝组织中Livin蛋白的表达;光镜下计数阳性细胞数并根据不同临床特征进行统计学分析。结果肝癌组织中Livin蛋白的表达明显高于正常肝组织(P<0.001);Livin蛋白的表达与患者的性别、年龄以及是否患有乙肝、丙肝、TNM临床分期均无明显关系,而与肝癌是否发生转移有明显关系;肝癌发生转移者Livin蛋白的表达率明显高于未转移者(P<0.05)。结论Livin蛋白的过度表达可能在肝癌的发生、发展中起重要作用,并与肝癌的转移密切相关。
出处 《中国普通外科杂志》 CAS CSCD 2008年第7期711-713,共3页 China Journal of General Surgery
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