鞘脂合成的中间代谢酶类的研究进展

The progress of enzymes of metabolic intermediate product in sphingolipid synthesis

鞘脂类是真核细胞膜上普遍存在的组份,它在真核细胞的胞吞、胞饮、信号转导、细胞的生长、凋亡、分化、衰老等过程中起着非常重要的作用。本文介绍了近年来鞘脂类代谢过程中的主要酶的结构与功能以及鞘脂在真核细胞中的转运机制。

Sphingolipids are ubiquitous of components of eukaryotic cell membranes, where they play important roles in intracellular endocytosis, endocytose, signaling transduction and in cell growth, apoptosis, differentiation, senescence, etc. The article describes about the structure of mainly enzymes in metabolism of sphingolipids and about function and transporting mechanism of sphingolipids in eucaryotic cell, recent years.