稀土离子对红细胞膜Ca^(2+)-ATP酶活性和ATP分解的影响

EFFECTS OF RARE EARTHS ON THE ACTIVITY OF CRYTHROCYTIC MEMBRANE Ca^(2+)-ATPase AND ATP DECOMPOSITION

研究了稀土离子对红细胞膜Ca2+－ATP酶活性和ATP分解的影响．实验结果表明，0．01mmol·dm-3的La3+、Sm3+、Y3+对红细胞膜Ca2+－ATP酶有激活作用，Y3+的激活作用小于Sm3+、La3+．当溶液中La3+、Sm3+、Y3+浓度增大时，稀土离子对Ca2+-ATP酶的激活作用反而减弱，抑制作用增强．稀土离子能加速溶液中ATP的分解，溶液中稀土离子浓度越高或作用时间越长，ATP分解越多．

It was studied that the effects of rare earths on the activity of crythrocytic mem-brane Ca2+-ATPase and the ATP decomposition in solution in this paper. The resultsshowed that 0. 01mmol. dm-s La3+,Sm3+,ys+ stimulated the activity of crythrocytic mem-brane Caz+-ATPase, but the stimulation of Y3+ was lower than that of La3+,Sm3+. WhenLa3+,Sm3+, Y3+ concentration increased in medium,their stimulation to Ca2+-ATPase activ-ity decreased,and the inhibition strengthened. The rare earth ions could activate the ATP de-compositon in solutibn,and the more their concentration or the longer the action time,themore the ATP decomposition.