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KAI1基因与恶性肿瘤浸润转移机制关系的研究进展

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摘要 浸润转移是恶性肿瘤的重要特性,也是引起肿瘤患者死亡的主要原因。尽管肿瘤的诊断和治疗水平不断改进,但总的治疗效果并不令人满意,其根本原因在于无法控制肿瘤的浸润和转移。随着分子生物学的深入研究,人们认识到肿瘤转移与肿瘤发生一样是由多种基因调控的,不仅有转移促进基因的激活,还伴有转移抑制基因的失活。目前,肿瘤分子生物学的研究热点逐渐转入分离和克隆肿瘤转移基因与转移抑制基因,期望通过揭示肿瘤转移在基因水平的本质,为改进肿瘤的诊断和治疗手段提供依据。
作者 朱婷 李群
出处 《实用药物与临床》 CAS 2008年第4期235-238,共4页 Practical Pharmacy and Clinical Remedies
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参考文献28

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