期刊文献+

高血压并阻塞性睡眠呼吸暂停综合征与颈动脉硬化的对比研究 被引量:8

下载PDF
导出
摘要 目的观察高血压(essential hypertension,EH)合并阻塞性睡眠呼吸暂停综合征(obstructive sleepapnea syndrome,OSAS)与高血压患者颈动脉内中膜厚度(intima-media thickness,IMT)及斑块的发生率。方法自2006年12月至2007年10月,60例经门诊测量血压并先后接受多导睡眠仪监测符合标准者入选本研究。根据监测结果分为:正常对照组、EH组、EH合并OSAS组(EH+OSAS)、OSAS组。结果与正常对照组相比,OSAS组与EH组患者均有颈动脉IMT增加及颈动脉斑块增加;与EH组及OSAS组相比,EH+OSAS组颈动脉IMT及颈动脉内斑块发生率明显增加。结论OSAS是引起的颈动脉硬化的一个独立危险因素。
出处 《中国医刊》 CAS 2008年第8期56-57,共2页 Chinese Journal of Medicine
  • 相关文献

参考文献9

  • 1Peker Y, Hedner J, Norum J, et al. Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea [J]. Am J Respir Crit Care Med, 2002,166: 159 -165.
  • 2Pipitone S, Corrado E,Muratori I, et al. Extracoronary atherosclerosis in patients with chronic ischemic heart disease : relationship with risk factors and the severity of coronary artery disease [ J ]. International Angiology ,2007,26,346 - 353.
  • 3刘力生.2004年中国高血压防治指南(实用本)[J].中华心血管病杂志,2004,32(12):1060-1064. 被引量:2619
  • 4Mathias WJ,Tsutsui JM,Andrade JL,et al. Value of rapid betablocker injection at peak dobutamine atropine stress echocardiography for detection of coronary artery disease [J]. J Am coll Cardiol,2003, 41:1583 - 1589.
  • 5Touboul P-J, Elbaz A, Koller C, et al. Common carotid artery intimamedia thickness and brain infarction : the Etude du Profil Genetique del' Infarctus Cerebral ( GENIC ) case-control study [ J ]. Circulation,2000,102:313 -318.
  • 6Baldassarre D, Amato M, Bondioli A, et al. Carotid artery intimamedia thickness measured by ultrasonography in normal clinical practice correlates well with atherosclerosis risk factors [ J ]. Stroke, 2000,31 : 2426 - 2430.
  • 7LAVIE L. Obstructive sleep apnea an oxidative stress disorder[ J]. Sleep Med Rev,2003,7 ( 1 ) :35 -51.
  • 8赵蕾,叶红,何秉贤.阻塞性睡眠呼吸暂停低通气综合征患者CRP的研究[J].中国医刊,2007,42(4):29-30. 被引量:3
  • 9鄂立平,李海燕.冠心病患者糖耐量减低与颈动脉粥样硬化的相关分析[J].中国医刊,2007,42(4):41-43. 被引量:3

二级参考文献19

  • 1宋文宣,王大鹏.C反应蛋白与冠心病[J].中国医刊,2004,39(8):8-11. 被引量:18
  • 2李光伟,Step.,L.检测人群胰岛素敏感性的一项新指数[J].中华内科杂志,1993,32(10):656-660. 被引量:2125
  • 3潘孝仁.高胰岛素血症、高血糖与高血压、冠心病的关系[J].中华内分泌代谢杂志,1993,9(4):239-240. 被引量:29
  • 4Nieto FJ, Young TB, Lind BK, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health[J]. JAMA,2000,283:1829 -1836.
  • 5Somers VK, Dyken ME, Clary MP, et al. Sympathetic neural mechanisms in obstructive sleep apnea [ J ]. J Clin Invest, 1995,96:1897 - 1904.
  • 6Shamsuzzaman AS, Winnicki M, Lanfranchi P, et al. Elevated C-reactive protein in patients with obstructive sleep apnea [ J ]. Cireulation,2002,105(21 ) : 2462 -2464.
  • 7Meier-Ewert HK, Ridker PM, Rifai N, et al. Effect of sleep loss on C-Reactive protein, an inflammatory marker of cardiovascular risk[J]. J Am Coll Cardiol,2004,43(4) : 678 -683.
  • 8Hayashi M, Fujimoto K, Urushibata K,et al. Hypoxia-sensitive molecules may modulate the development of atherosclerosis in sleep apnoea syndrome [ J ]. Respirology ,2006,11 ( 1 ) : 24 - 31.
  • 9Kokturk O, Ciftci TU, Mollarecep E, et al. Elevated C-reactive protein levels and increased cardiovascular risk in patients with obstructive sleep apnea syndrome[J]. Int Heart J,2005,46(5):801 -809.
  • 10Minoguchi K, Yokoe T, Tazaki T, et al. Increased carotid intimamedia thickness and serum inflammatory markers in obstructive sleepapnea[J]. Am J Respir Crit Care Med,2005,172(5):625 -630.

共引文献2621

同被引文献69

引证文献8

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部