从海洋沉积物分离的产抗菌素和环肽的放线菌

Isolation and Characterization of A Strain of Bioactive Marine Actinomycete

从海洋沉积物分离的产抗菌素和环肽的放线菌周世宁姜广策吴雄宇林永成（中山大学生物化学系／应用化学系，广州５１０２７５）关键词抗菌素，环肽，放线菌，海洋微生物分类号Ｑ９３从陆地微生物寻找抗菌素药物的成功率已大大下降，而海洋微生物作为药物的新来源，正受到世...

A strain of actinimycete,designated as ZS110,was isolated from marine sediment from the South China Sea.The strain ZS110 was characterized morphologically and physiologically.One antibiotic and five cyclopeptides were separated from the fermentation broth of the isolate ZS110.Some factors for the growth of the strain and the formation of bioative substance were investigated.The antibiotic substance exhibited inhibitory activity against the growth of all Gram positive indicator bacteria.