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透析患者出血性疾病的诊断与治疗 被引量:3

Diagnosis and treatment of hemorrhagic disease in patients undergoing dialysis
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摘要 出血性疾病是透析患者常见的严重并发症之一。各种因素导致的血小板功能异常是引起尿毒症患者出血的主要原因,多表现为出血时间延长。充分透析,积极纠正贫血可以预防及治疗尿毒症患者的出血。可以采用去氨加压素、雌激素和冷沉淀等药物治疗。临床上还需要重视与尿毒症治疗相关的出血性疾病,包括抗凝剂过量导致的出血性疾病及肝素诱导血小板减少。 Hemorrhagic disease is one of the most serious complications in patients undergoing dialysis. The primary cause is platelets dysfunction that Results from various kinds of factors. Prolonged bleeding time (BT) is the most common laboratory abnormality. Adequate dialysis and correction of anemia would prevent and treat hemorrhagic diseases. Several medications, such as 1-desamino-8-D-arginine vasopressin (dDAVP) , estrogen and cryoprecipitate, are useful treatment options. Hemorrhagic disease derived from overload of anticoagulants and heparin-induced thrombocytopenia (HIT) , which Results from the treatment of uremia, should also be carefully recognized and treated.
作者 王莉
出处 《实用医院临床杂志》 2008年第4期31-33,共3页 Practical Journal of Clinical Medicine
关键词 尿毒症 透析 出血性疾病 诊断 治疗 Uremia Dialysis Hemorrhagic disease Diagnosis Treatment
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参考文献14

  • 1[1]Molino D,Lucia D,Santo NG.Coagulation disorders in uremia[J].Se-min Nephrol,2006,26(3):46.
  • 2[2]Remuzzi G,Perico N,Zoja C,et al.Role of endothelium-derived nitric ox-ide in the bleeding tendency of uremia[J].J Clin Invest,1990,86 (5):1768-1771.
  • 3[3]Nenci GG,Berrettini M,Agnelli G.Effect of peritoneal dialysis,haemodi-alysis and kidney transplantation on blood platelet function.I.Platclet aggregation by ADP and epinephrine[J].Nephron,1979,23(6):287-292.
  • 4[4]Diaz RM,Etebanell E,Cases A.Erythropoietin improves signaling through tyrosine phesphorylation in platelets from uremic patients[J].Thromb Haemost,1999,82(4):1312-1317.
  • 5[5]Zhou X J,Vaziri ND.Defective calcium signalling in uraemie platelets and its amelioration with long-term erythropoietin therapy[J].Nephrol Dial Transplant,2002,17(6):992-997.
  • 6[6]Zeigler ZR,Megaludis A,Fraley DS.Desmopressin (d-DAVP) effects on platelet rheology and yon Willebrand factor activities in uremia[J].Am J Hematol,1992,39(2):90-95.
  • 7[7]Livio M,Mannucci PM,Vigano G.Conjugated estrogens for the manage-ment of bleeding associated with renal failure[J].N Engl J Med,1986,315(12):731-735.
  • 8[8]Heistinger M,Stockenhuber F,Schneider B.Effect of conjugated estrogens on platelet function and prostacyclin generation in CRF[J].Kidney Int,1990,38(6):1181-1186.
  • 9[9]Vigano G,Gaspari F,Loatelli M.Doso-effect and pharmacokinetics of es-trogens given to correct bleeding time in uremia[J].Kidney Int,1988,34(6):853-858.
  • 10[10]Janson PA,Jubelirer SJ,Weinstein MJ.Treatment of the bleeding tenden-cy in uremia with cryoprecipitate[J].N Engl J Med,1980,303(23):1318-1322.

同被引文献30

  • 1王秦,解汝娟,高春艳.磷脂酰丝氨酸及其结合配体与尿毒症血液高凝状态的相关性[J].中华临床医师杂志(电子版),2012,6(16):4825-4827. 被引量:3
  • 2姜埃利,马腾骧.肾衰长期血液透析肾囊肿与肾肿瘤的发生[J].中华肿瘤杂志,1995,17(3):202-204. 被引量:5
  • 3Mocanu C, BarSscu D, Marinescu F, IAcreanu M, Iliooi F, Simi- onescu C. Neovascular glaucoma--retrospective study[ J]. Oph- thalmology,2005,49(4) :58-55.
  • 4Levy J, Tovbin D, Lifshitz T, Zlotnik M, Tessler Z. Intraocular pressure during haemodialysis: a review[J]. Eye ( Lond), 2005, 19(12) :1249-1256.
  • 5Tovbin D, Belfair N, Shapira S, Rosenthal G, Friger M, Feldman L, et al. High postdialysis urea rebound can predict intradialytic increase in intraocular pressure in dialysis patients with lowered intradialytic hemoconcentration [ J ]. Nephron, 2002,90 ( 2 ) : 181 - 187.
  • 6Tawara A, Kobata H, Fujisawa K, Abe T, Ohnishi Y. Mechanism of intraocular pressure elevation during hemodialysis [ J ]. Curt Eye Re8,1998,17 ( 4 ) : 339-347.
  • 7Ghaffariyeh A,Honarpisheh N, Pishva E. High vitreous urea re- bound in a glaucoma patient with increased intraocular pressure during hemodialysis [ J ]. Can J Ophthalmol , 2009,44 ( 5 ) : e51.
  • 8Gomes CM, Lucon AM, Yamada RT, Gomes MC, Arap S. Rare complication of an arteriovenous fistula for dialysis: glaucoma [J]. Scand J Urol Nephrol,2000,34( 3 ) :219-221.
  • 9Song WK, Ha S J, Yeom HY, Seoung G J, Hong YJ. Recurrent in- traocular pressure elevation during hemodialysis in a patient with neovascular glaucoma [ J ]. Korean J Ophtkalmol, 2006,20 (2) :109-112.
  • 10Yazdani S,Hendi K,Pakravan M, Mahdavi M, Yaseri M. Intravit- real bevacizumab for neovascular glaucoma:a randomized con- trolled trial[ J]. J Glaucoma ,2009,18 (8) :532-537.

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